The Science Comedian was featured in the local newspaper a few days ago.
He is Brian Malow and his site is ScienceComedian.com.
Blog“Malow's jokes really are for everyone, not just scientists. In fact, because he often performs for audiences with mixed backgrounds in the sciences or no background in the sciences at all, he is happy to assume the role of an on-stage teacher, providing his audiences with just enough scientific background to get the joke.”
Chemical & Engineering News
“Thanks for the opportunity to laugh at infectious disease and not feel guilty.”
Chris Condayan, American Society for Microbiology
He links to the Bad Astronomy blog, so he can't be all bad.
I can't vouch for the quality. Never partaken. But, it just seems like the world needs more science comedians.