I think Charles is asking about the observational support for universal isotropy. The ultimate support for this is the uniformity of the cosmic microwave background, which has indeed been measured in "the opposite direction" as well as left, right, up, down, and everything in between. It turns out to be uniform to 1 part in 100,000. Highly isotropic! Since that time, gravity has resulted in localized anisotropies, but it has done so similarly throughout the universe.
Originally Posted by Charles Olsen
Here is a somewhat-related paper by Collins and Hawking -- Why Is the Universe Isotropic?
Everyone is entitled to his own opinion, but not his own facts.