This is a little unclear. Orion is a grouping of stars at greatly varying distances from Earth, and I suspect Cassiopea is the same. I know some constellations are actually made up of stars that are loosely bound together - Ursa Major is one, I believe.
Cassiopeia is home to a vast cloud, and so is Orion, both constellations being dwarfed by their molecular clouds. The Orion molecular cloud spans most of Orion, Taurus, Gemini and Canis Major.
Where in relation to these constellations' stars are these clouds?
"In the nightgown of the sullen moon, How the windows lean into the room, In the nightgown of the sullen moon."
-They Might Be Giants