Even when the system collapses socioeconomically, technology tends to stick around and evolve further, because of necessity. Even the medieval period was more technologically advanced than classical civilization. There were important advances in metallurgy, chemistry (alchemy), mechines and agriculture. The system of slavery in the Roman era was actually bad for technological development. So I think the Moon landing will definitely be remembered, as the first time humans set foot on another world, for as long as human civilization exists continuously on this planet, the reason being that the recording technology is much more developed now than it was in ancient times and historical records should be much more accurate a thousand years from now, and even if civilization collapses, the technology will remain and will be kept alive by the technici.
As far as the topic goes, it does seem like a natural progression of life from the ocean, to land to space. But then there's also the "inward looking" philosophy that Ilya mentions, and this could mean science becoming more theoretical and less empirical. I.e. it becomes more interesting to explore the inner world of ideas and possibilities, than to explore the physical universe of actualities.
Paradoxically, it may be that a very advanced theoretical physics is needed to make inter-stellar travel feasible, and that a more inward looking social order is necessary for such theoretical advancement to develop in the first place.